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Patent · US6261820B1 · B1 · US

Fibronolytically active polypeptide

(11) Publication number
US6261820B1
(21) Application number
US-41132999-A
(22) Filing date
1999-10-01
(30) Priority date
1999-10-01
(43) Publication date
2001-07-17
(45) Date of grant
2001-07-17
(52) CPC
  • C12N Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media: 9/6489, 9/6418
  • A61K Preparations for medical, dental or toiletry purposes: 38/1703
  • A61P Specific therapeutic activity of chemical compounds or medicinal preparations: 7/00, 7/02
  • C07K Peptides: 14/00
(73) Assignee
AMGEN INC
(54) Title
Fibronolytically active polypeptide
(57) Abstract

A fibrinolytically active metalloproteinase polypeptide (called "novel acting thrombolytic") which is useful for blood clot lysis in vivo and methods and materials for its production by recombinant expression are described.

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Claims (2)

  1. A fibrinolytically active polypeptide having the amino acid sequence of SEQ ID NO: 1.
  2. The polypeptide of claim 1 which has been made by recombinant expression in yeast.

Citations (2)

  • EP0323722A1
  • US4610879A
Record as JSON 
{
  "publication_number": "US6261820B1",
  "country": "US",
  "kind": "B1",
  "title": "Fibronolytically active polypeptide",
  "abstract": "A fibrinolytically active metalloproteinase polypeptide (called \"novel acting thrombolytic\") which is useful for blood clot lysis in vivo and methods and materials for its production by recombinant expression are described.",
  "claims": [
    "1. A fibrinolytically active polypeptide having the amino acid sequence of SEQ ID NO: 1.",
    "2. The polypeptide of claim 1 which has been made by recombinant expression in yeast."
  ],
  "cpc": [
    "C12N 9/6489",
    "A61K 38/1703",
    "A61P 7/00",
    "A61P 7/02",
    "C07K 14/00",
    "C12N 9/6418"
  ],
  "assignees": [
    "AMGEN INC"
  ],
  "filing_date": "1999-10-01",
  "publication_date": "2001-07-17",
  "grant_date": "2001-07-17",
  "priority_date": "1999-10-01",
  "application_number": "US-41132999-A",
  "family_id": "23628486",
  "citations": [
    "EP0323722A1",
    "US4610879A"
  ]
}

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