fibroblast growth factor 1
Term · Agriculture and food · MLC-T-AGR-002482
A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. It binds to heparin, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (fibroblast growth factor 2).
| Identifier | MLC-T-AGR-002482 |
|---|---|
| Field | Agriculture and food |
| Subject | Fields of Study |
| Synonyms | acidic fibroblast growth factor; fibroblast growth factor, acidic; fibroblast growth factor-1 |
| References | Medical Subject Headings; NAL Agricultural Thesaurus and Glossary |
| See also | fibroblast growth factors |
| Translations | Spanish: factor 1 de crecimiento de fibroblasto |
Record as JSON
{
"id": "MLC-T-AGR-002482",
"term": "fibroblast growth factor 1",
"field": "Agriculture and food",
"definition": "A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. It binds to heparin, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (fibroblast growth factor 2).",
"synonyms": [
"acidic fibroblast growth factor",
"fibroblast growth factor, acidic",
"fibroblast growth factor-1"
],
"subject": "Fields of Study",
"see_also": [
"fibroblast growth factors"
],
"references": [
"Medical Subject Headings",
"NAL Agricultural Thesaurus and Glossary"
],
"translations": {
"es": "factor 1 de crecimiento de fibroblasto"
},
"url": "https://mlchart.com/terminology/agriculture/fibroblast-growth-factor-1/"
}
Record 2,482 of 6,908 in Agriculture and food terminology (MLC-0114). Request the full dataset.