Insertional mutagenesis

{
  "id": "MLC-T-AGR-003460",
  "term": "Insertional mutagenesis",
  "field": "Agriculture and food",
  "definition": "Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt genetic translation of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.",
  "subject": "Fields of Study",
  "see_also": [
    "mutagenesis",
    "interspersed repetitive sequences",
    "gene targeting",
    "repetitive sequences"
  ],
  "references": [
    "Medical Subject Headings 2012",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "mutagénesis insercional"
  },
  "url": "https://mlchart.com/terminology/agriculture/insertional-mutagenesis/"
}