low density lipoprotein receptors

{
  "id": "MLC-T-AGR-003851",
  "term": "low density lipoprotein receptors",
  "field": "Agriculture and food",
  "definition": "Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.",
  "synonyms": [
    "LDL (low density lipoprotein) receptors",
    "LDL receptors",
    "lipoprotein LDL receptors"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "lipoprotein receptors"
  ],
  "references": [
    "Medical Subject Headings 2018",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "receptores de lipoproteínas de baja densidad"
  },
  "url": "https://mlchart.com/terminology/agriculture/low-density-lipoprotein-receptors/"
}