simvastatin

{
  "id": "MLC-T-AGR-005829",
  "term": "simvastatin",
  "field": "Agriculture and food",
  "definition": "A derivative of lovastatin and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase (hydroxymethylglutaryl CoA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL receptors, it increases breakdown of LDL cholesterol.",
  "subject": "Research, Technology, Methods",
  "see_also": [
    "lovastatin",
    "low density lipoprotein cholesterol"
  ],
  "references": [
    "Medical Subject Headings",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "simvastatina"
  },
  "url": "https://mlchart.com/terminology/agriculture/simvastatin/"
}