| VAQ | Visual Air Quality |
| VAV | Variable Air Volume System |
| VC | Vibrio cholerae; Vital Capacity |
| VCS | Voluntary Consensus Standard |
| VCTM | Virtual Tissue Model |
| VDL | Variable Density Log |
| VE | Value Engineering |
| VEE | Venezuelan Equine Encephalomyelitis |
| Vehicle-Specific 5-Cycle CO2 | Vehicle-Specific 5-Cycle Carbon Dioxide |
| v-Embryo™ | Virtual Embryo |
| VER | Calibration Verification Standard |
| VFAR | virulence-factor activity relationship |
| VFD | Variable Frequency Drive |
| VHAP | Volatile Hazardous Air Pollutant |
| VHAP Concentration | Volatile Hazardous Air Pollutant Concentration |
| VHAP of Potential Concern | Volatile Hazardous Air Pollutant of Potential Concern |
| VHF | Viral Hemorrhagic Fevers |
| VISTAS | Visibility Improvement State and Tribal Association of the Southeast |
| v-Liver™ | Virtual Liver |
| VMT | Vehicle miles traveled; Vehicle Miles Travelled |
| VNBC | viable but not (non-) culturable (bacteria) |
| VO Concentration | Volatile Organic Concentration |
| VO2 | Oxygen consumption |
| VOC | Volatile Organic Compounds |
| VOC Content | Volatile Organic Compound Content |
| VOC Emission | Volatile Organic Compound Emission |
| VOC Emission Control Device | Volatile Organic Compound Emission Control Device |
| VOC Emission Reduction System | Volatile Organic Compound Emission Reduction System |
| VOC Solvent | Volatile Organic Compound Solvent |
| VOC Used | Volatile Organic Compound Used |
| VOCs | Volatile Organic Chemicals; Volatile Organic Pollutants |
| VOHAP | Volatile Organic Hazardous Air Pollutant |
| VOHAP Concentration | Volatile Organic Hazardous Air Pollutant Concentration |
| VOL | Volatile Organic Liquid |
| VP | vapor pressure |
| VPP | Variable Peak Pricing |
| VR | Ventilation Rate |
| VRU | Vapor Recovery System |
| VS | Volatile Solids |
| VSAT | Vulnerability Self Assessment Tool |
| VSL | Value of Statistical Life |
| VSLY | Value of statistical life year |
| VSOC | Volatile Synthetic Organic Chemicals |
| VSPZ | Vegetation and Soil Protection Zone |
| VSS Process | Vertical Stud Soderberg Process |
| VT | Tidal Volume |