Benchmark Dose

{
  "id": "MLC-T-ENV-002963",
  "term": "Benchmark Dose",
  "field": "Environment",
  "definition": "1. A dose or concentration that produces a predetermined change in response rate of an adverse effect (called the benchmark response or BMR) compared to background.\n\n2. A dose that produces a predetermined change in response rate of an adverse effect (called the benchmark response or BMR) compared to background.\n\n3. An exposure due to a dose of a substance associated with a specified low incidence of risk, generally in the range of 1% to 10%, of a health effect; or the dose associated with a specified measure or change of a biological effect.\n\n4. A dose or concentration that produces a predetermined change in response rate of an adverse effect (called the benchmark response or BMR) compared to background. See IRIS Glossary. A dose of a substance that when ingested produces a predetermined change in the response rate of an adverse effect relative to the background response rate of this effect. This predetermined change is called a “benchmark response” or BMR. See Benchmark Dose Technical Guidance (EPA, 2012). See Benchmark Dose Technical Guidance (EPA, 2012).",
  "abbreviation": "BMD",
  "subject": "Science and research",
  "see_also": [
    "Benchmark Concentration"
  ],
  "references": [
    "Integrated Risk Information System (IRIS) Glossary; EPA 2003",
    "Risk Assessment Glossary",
    "Benchmark Dose Software (BMDS) Glossary of Terms",
    "Health Effects Notebook Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/benchmark-dose/"
}