Benchmark dose

{
  "id": "MLC-T-CHM-001183",
  "term": "Benchmark dose",
  "field": "Chemistry",
  "definition": "A dose that produces a predetermined change in response, known as the benchmark response, in a specified proportion of the exposed population, typically 5% or 10%, compared to a control group. It is calculated from dose-response data using mathematical modeling. This value serves as a point of departure for establishing regulatory exposure limits.",
  "synonyms": [
    "lower effective dose"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "dose",
    "risk"
  ],
  "references": [
    "PAC, 2001, 73, 993. 'Risk assessment for occupational exposure to chemicals. A review of current methodology (IUPAC Technical Report)' on page 1021 (https://doi.org/10.1351/pac200173060993)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/benchmark-dose/"
}