Lowest effective dose

{
  "id": "MLC-T-CHM-006788",
  "term": "Lowest effective dose",
  "field": "Chemistry",
  "definition": "The smallest dose of a substance that produces a statistically significant and biologically relevant effect in a test system or population. This dose is typically determined from dose-response studies and represents the threshold at which a measurable positive outcome is observed. It is a key parameter in pharmacology and toxicology for assessing efficacy or toxicity.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 908 (https://doi.org/10.1351/PAC-REC-08-07-09)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/lowest-effective-dose/"
}