MLchartDataset catalogue

Cholinesterase inhibitor

Term · Environment · MLC-T-ENV-004941

Drugs that inhibit cholinesterases. The neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.

Table 1. Record
IdentifierMLC-T-ENV-004941
FieldEnvironment
SubjectBiological substances
ReferencesNLM Medical Subject Headings (MeSH)
Record as JSON
{
  "id": "MLC-T-ENV-004941",
  "term": "Cholinesterase inhibitor",
  "field": "Environment",
  "term_source": "Cholinesterase Inhibitor",
  "definition": "Drugs that inhibit cholinesterases. The neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.",
  "subject": "Biological substances",
  "references": [
    "NLM Medical Subject Headings (MeSH)"
  ],
  "url": "https://mlchart.com/terminology/environment/cholinesterase-inhibitor/"
}

Record 4,842 of 29,894 in Environment terminology (MLC-0121). Request the full dataset.