Cumulative Toxicity

{
  "id": "MLC-T-ENV-007090",
  "term": "Cumulative Toxicity",
  "field": "Environment",
  "definition": "1. Adverse effects of repeated exposures occurring as a result of prolonged action or increased concentration of the administered test substance or its metabolites in the susceptible tissues.\n\n2. Adverse effects of repeated doses occurring as a result of prolonged action on, or increased concentration of the administered test substance or its metabolites in susceptible tissues. [40 CFR 798.2250 (CFR 2013)]",
  "references": [
    "40 CFR 79.61 (CFR 2013)",
    "40 CFR 798.2450 (CFR 2013)"
  ],
  "url": "https://mlchart.com/terminology/environment/cumulative-toxicity/"
}