MLchartDataset catalogue

Histone deacetylation

Term · Environment · MLC-T-ENV-013352

Histone Deacetylation is the covalent post-translational enzymatic addition of an acetyl group(s) to a histone protein. By exposing cationic sites on the protein that promote ionic interaction with the negatively charged DNA backbone, Histone Deacetylation induces DNA condensation and regulates genetic functions, such as transcription.

Table 1. Record
IdentifierMLC-T-ENV-013352
FieldEnvironment
SubjectBiological substances
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ENV-013352",
  "term": "Histone deacetylation",
  "field": "Environment",
  "term_source": "Histone Deacetylation",
  "definition": "Histone Deacetylation is the covalent post-translational enzymatic addition of an acetyl group(s) to a histone protein. By exposing cationic sites on the protein that promote ionic interaction with the negatively charged DNA backbone, Histone Deacetylation induces DNA condensation and regulates genetic functions, such as transcription.",
  "subject": "Biological substances",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/histone-deacetylation/"
}

Record 13,021 of 29,894 in Environment terminology (MLC-0121). Request the full dataset.