Histones

{
  "id": "MLC-T-ENV-013353",
  "term": "Histones",
  "field": "Environment",
  "definition": "1. Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.\n\n2. A type of protein present in the nucleus of eukaryotic cells that helps to compact DNA into tightly packed chromosomes.\n\n3. A type of protein found in chromosomes; histones attached to DNA resemble \"beads on a string.\"",
  "references": [
    "NLM Medical Subject Headings (MeSH)",
    "NOAA Coral Reef Glossary",
    "NIH National Institute of General Medical Sciences Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/histones/"
}