Quantitative Structure Activity Relationship

{
  "id": "MLC-T-ENV-022932",
  "term": "Quantitative Structure Activity Relationship",
  "field": "Environment",
  "definitions": [
    "1. Mathematical relationship between a property (activity) of a chemical and a number of descriptors of the chemical. These descriptors are chemical or physical characteristics obtained experimentally or predicted from the structure of the chemical.\n\n2. A mathematical relationship between a quantifiable aspect of chemical structure and a chemical property or reactivity or a well defined biological activity, such as toxicity. Using a sample set of chemicals, a relationship is established between one or many physical-chemical properties a chemical possesses... due to its structure and a chemical property or biological activity of concern. This mathematical expression is then used to predict the chemical property or biological response expected from other chemicals with similar structures. It is based on the presumption that similar molecules or chemical structures have similar properties or biological activities or toxicity potential.",
    "A mathematical relationship between a quantifiable aspect of chemical structure and a chemical property or reactivity or a well defined biological activity, such as toxicity. Using a sample set of chemicals, a relationship is established between one or many physical-chemical properties a chemical possesses due to its structure and a chemical property or biological activity of concern. This mathematical expression is then used to predict the chemical property or biological response expected from other chemicals with similar structures. It is based on the presumption that similar molecules or chemical structures have similar properties or biological activities or toxicity potential. Read about the principles that OECD has developed to facilitate the appropriate use of QSAR modeling for regulatory purposes."
  ],
  "abbreviation": "QSAR",
  "subject": [
    "Chemical substances",
    "Chemicals, toxics and pesticides"
  ],
  "references": [
    "40 CFR 132.2 (CFR 2013); 40 CFR Appendix C to Part 132 (CFR 2013)",
    "Toxicity Testing and Risk Assessment Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/quantitative-structure-activity-relationship/"
}