5-FITC-labeled colon-heptapeptide

{
  "id": "MLC-T-ONC-009550",
  "term": "5-FITC-labeled colon-heptapeptide",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate consisting of a 7 amino acid peptide sequence, KCCFPAQ, that specifically targets human colon cancer and labeled, via the linker, GGGSK, with the fluorescent dye, fluorescein isothiocyanate (5-FITC), with potential imaging activity. Following spray application to the colon wall during colonoscopy in areas that look abnormal, the colon heptapeptide moiety of 5-FITC-labeled colon-heptapeptide specifically targets and binds to a cell surface target overexpressed on pre-cancerous or cancerous colon cells. Upon internalization, the FITC moiety allows for fluorescent imaging and the area of interest for biopsies can then be visualized.",
  "synonyms": [
    "KCCFPAQ-GGGSK-(5-FITC)-NH2",
    "KCC colon heptapeptide"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/5-fitc-labeled-colon-heptapeptide/"
}