MLchartDataset catalogue

IRDye800CW-labeled heptapeptide KSP-910638G

Term · Oncology and biomedicine · MLC-T-ONC-014569

An imaging agent composed of a heptapeptide targeting human epithelial growth factor receptor type 2 (EGFR2; HER2; ErbB2) conjugated, via a five-amino acid linker, to the near-infrared (NIR) fluorescent dye IRDye800CW, that can potentially be used for the imaging of HER2-expressing tumors. Upon oral administration of the IRDye800CW-labeled heptapeptide KSP-910638G, the peptide moiety targets and binds to HER2 expressed on tumor cells in the gastrointestinal (GI) tract. Upon fluorescence imaging of the fluorophore IRDye800CW, the tumor cells can be detected.

Table 1. Record
IdentifierMLC-T-ONC-014569
FieldOncology and biomedicine
SynonymsKSP heptapeptide; KSP-910638G heptapeptide
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014569",
  "term": "IRDye800CW-labeled heptapeptide KSP-910638G",
  "field": "Oncology and biomedicine",
  "definition": "An imaging agent composed of a heptapeptide targeting human epithelial growth factor receptor type 2 (EGFR2; HER2; ErbB2) conjugated, via a five-amino acid linker, to the near-infrared (NIR) fluorescent dye IRDye800CW, that can potentially be used for the imaging of HER2-expressing tumors. Upon oral administration of the IRDye800CW-labeled heptapeptide KSP-910638G, the peptide moiety targets and binds to HER2 expressed on tumor cells in the gastrointestinal (GI) tract. Upon fluorescence imaging of the fluorophore IRDye800CW, the tumor cells can be detected.",
  "synonyms": [
    "KSP heptapeptide",
    "KSP-910638G heptapeptide"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/irdye800cw-labeled-heptapeptide-ksp-910638g/"
}

Record 9,567 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.