anti-immunoglobulin-beta CAR T Cells

{
  "id": "MLC-T-ONC-010821",
  "term": "anti-immunoglobulin-beta CAR T Cells",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of T lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) targeting immunoglobulin-beta (Igb), with potential immunostimulating and antineoplastic activities. Upon administration, the anti-Igb CAR T cells are directed to, specifically bind to, and induce selective toxicity in Igb antigen-expressing tumor cells.",
  "synonyms": [
    "anti-Igb CAR T cells",
    "shRNA-IL-6-modified anti-CD19 CAR-T cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-immunoglobulin-beta-car-t-cells/"
}