AR antagonist BMS-641988

{
  "id": "MLC-T-ONC-011217",
  "term": "AR antagonist BMS-641988",
  "field": "Oncology and biomedicine",
  "definition": "An androgen receptor (AR) antagonist with potential antineoplastic and anti-androgenic activities. BMS-641988 binds to the androgen receptor in target tissues, thereby preventing androgen-induced receptor activation, and facilitates the formation of inactive complexes that cannot be translocated to the nucleus. This may inhibit androgen-dependent gene expression, subsequently leading to an inhibition of cell growth and apoptosis in AR-expressing cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ar-antagonist-bms-641988/"
}