Aurora A kinase inhibitor LY3295668

{
  "id": "MLC-T-ONC-011299",
  "term": "Aurora A kinase inhibitor LY3295668",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable inhibitor of the serine/threonine protein kinase aurora A, with potential antimitotic and antineoplastic activities. Upon administration, aurora A kinase inhibitor LY3295668 targets, binds to and inhibits the activity of aurora A kinase. This may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, inhibition of cell division and the induction of apoptosis in cells overexpressing aurora A kinase. Aurora A kinase, overexpressed in a wide variety of cancers, plays an essential role in the regulation of spindle assembly and mitosis.",
  "synonyms": [
    "LY 3295668 erbumine",
    "LY-3295668 erbumine",
    "AK 01 erbumine",
    "LY3295668 erbumine",
    "aurora kinase A inhibitor LY3295668 erbumine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/aurora-a-kinase-inhibitor-ly3295668/"
}