autologous gene-modified PD-1-positive T lymphocytes Sc610

{
  "id": "MLC-T-ONC-011631",
  "term": "autologous gene-modified PD-1-positive T lymphocytes Sc610",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous programmed cell death protein 1 (PD-1; PDCD1; CD279)-positive T lymphocytes transduced with a lentiviral vector encoding for an as of yet undisclosed receptor, with potential immunostimulatory and antineoplastic activities. Upon administration, autologous gene-modified PD-1-positive T lymphocytes Sc610 bind to tumor cells expressing the antigen for the as of yet undisclosed receptor, which may result in specific cytotoxic T-lymphocyte (CTL)-mediated tumor cell killing.",
  "synonyms": [
    "autologous gene-modified PD-1-positive T cells Sc610"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-gene-modified-pd-1-positive-t-lymphocytes-sc610/"
}