autologous IL-7-expressing TILs ADP-TILIL7

{
  "id": "MLC-T-ONC-011668",
  "term": "autologous IL-7-expressing TILs ADP-TILIL7",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous tumor infiltrating lymphocytes (TILs) engineered to express the cytokine interleukin-7 (IL-7), with potential immunomodulating and antineoplastic activities. The TILs are isolated from an autologous tumor sample and transduced with a lentiviral vector to express IL-7. Upon infusion of the autologous IL-7-expressing TILs ADP-TILIL7 back into the patient, the TILs specifically recognize, target and kill the patient's tumor cells. IL-7 is a cytokine that promotes the proliferation and survival of T cells and may enhance the activity and durability of the TILs.",
  "synonyms": [
    "autologous engineered TILs ADP-TILIL7",
    "autologous IL-7-transduced TILs ADP-TILIL7",
    "autologous TILs expressing IL-7 ADP-TILIL7"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-il-7-expressing-tils-adp-tilil7/"
}