cromolyn sodium inhalant PA101

{
  "id": "MLC-T-ONC-012813",
  "term": "cromolyn sodium inhalant PA101",
  "field": "Oncology and biomedicine",
  "definition": "A solution containing a high concentration of cromolyn sodium, with potential mast cell stabilizing, anti-tussive and anti-inflammatory activities. Upon inhalation of PA101 via a nebulizer, cromolyn blocks calcium ion influx into mast cells, thereby preventing the degranulation of mast cells in the lungs. This blocks the release of pro-inflammatory mediators from mast cells, such as histamine and slow-reacting substance of anaphylaxis (SRS-A), and prevents both bronchoconstriction and an inflammatory response. In indolent systemic mastocytosis (ISM), PA101 may be able to reduce the symptoms associated with this disease.",
  "synonyms": [
    "sodium cromoglicate inhalant PA101"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cromolyn-sodium-inhalant-pa101/"
}