cytarabine liposome

{
  "id": "MLC-T-ONC-012879",
  "term": "cytarabine liposome",
  "field": "Oncology and biomedicine",
  "definition": "A liposomal intrathecal formulation of the antimetabolite cytarabine. As an S-phase-specific antimetabolite, cytarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; the incorporation of cytarabine triphosphate into DNA appears to inhibit DNA polymerase and so DNA synthesis, resulting in cell death.",
  "synonyms": [
    "cytarabine liposomal",
    "Liposomal Ara-C",
    "DepoFoam encapsulated cytarabine",
    "encapsulated cytarabine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cytarabine-liposome/"
}