FGF401 inhibitor FGF401

{
  "id": "MLC-T-ONC-013576",
  "term": "FGF401 inhibitor FGF401",
  "field": "Oncology and biomedicine",
  "definition": "An inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, FGF401 binds to and inhibits the activity of FGFR4, which leads to an inhibition of tumor cell proliferation in FGFR4-overexpressing cells. FGFR4 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cell proliferation, differentiation, angiogenesis, and survival.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fgf401-inhibitor-fgf401/"
}