ibrexafungerp

{
  "id": "MLC-T-ONC-014295",
  "term": "ibrexafungerp",
  "field": "Oncology and biomedicine",
  "definition": "An intravenous and orally bioavailable semisynthetic derivative of enfumafungin with potential antifungal activity. Upon administration, ibrexafungerp inhibits beta-1,3-D-glucan synthase, an enzyme essential for fungal cell wall synthesis. This results in weakening of the fungal cell wall, thereby leading to osmotic lysis and eventually fungal cell death.",
  "abbreviation": "IBX",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ibrexafungerp/"
}