MLchartDataset catalogue

Ifupinostat hydrochloride

Term · Oncology and biomedicine · MLC-T-ONC-014332

The hydrochloride salt form of ifupinostat,, an inhibitor of both phosphoinositide 3-kinase (PI3K) and histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon administration, ifupinostat binds to and inhibits the activity and mediated signaling of both PI3K and HDAC. In addition, ifupinostat may also inhibit other signaling pathways. This may prevent growth of PI3K and/or HDAC-expressing tumor cells.

Table 1. Record
IdentifierMLC-T-ONC-014332
FieldOncology and biomedicine
SynonymsBEBT-908 hydrochloride; PI3K/HDAC inhibitor BEBT-908
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014332",
  "term": "Ifupinostat hydrochloride",
  "field": "Oncology and biomedicine",
  "term_source": "Ifupinostat Hydrochloride",
  "definition": "The hydrochloride salt form of ifupinostat,, an inhibitor of both phosphoinositide 3-kinase (PI3K) and histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon administration, ifupinostat binds to and inhibits the activity and mediated signaling of both PI3K and HDAC. In addition, ifupinostat may also inhibit other signaling pathways. This may prevent growth of PI3K and/or HDAC-expressing tumor cells.",
  "synonyms": [
    "BEBT-908 hydrochloride",
    "PI3K/HDAC inhibitor BEBT-908"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ifupinostat-hydrochloride/"
}

Record 8,964 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.