Immediate-release bupropion

{
  "id": "MLC-T-ONC-014380",
  "term": "Immediate-release bupropion",
  "field": "Oncology and biomedicine",
  "definition": "An immediate-release (IR) tablet formulation of the aminoketone bupropion, with antidepressant activity and for potential use in promoting smoking cessation, increasing sexual desire, and reducing cancer-related fatigue. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine, and is a central nicotinic acetylcholine receptor antagonist. Bupropion may also reduce circulating levels of tumor necrosis factor (TNF) and normalize hypothalamic-pituitary-adrenal (HPA) axis functioning, which is dysregulated in certain cases of cancer-related fatigue.",
  "synonyms": [
    "IR bupropion",
    "bupropion immediate release"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/immediate-release-bupropion/"
}