Iolopride I-123

{
  "id": "MLC-T-ONC-014548",
  "term": "Iolopride I-123",
  "field": "Oncology and biomedicine",
  "definition": "A radiopharmaceutical containing the dopamine D2/D3 receptor agonist iodobenzamide (IBZM) labeled with the radionuclide iodine I 123 with dopamine receptor-binding and radioisotopic activities. Upon administration, iodine I 123 iodobenzamide binds to dopamine D2/D3 receptors; subsequently, tissues expressing these receptors can be visualized using single photon emission computed tomography (SPECT). Dopamine receptors are a class of metabotropic G protein-coupled receptors found in the central nervous system (CNS) and neuroendocrine tumors such as pheochromocytoma and paraganglioma.",
  "abbreviation": "123I-IBZM",
  "synonyms": [
    "iodine I 123 iodobenzamide"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/iolopride-i-123/"
}