MLchartDataset catalogue

ipomeanol

Term · Oncology and biomedicine · MLC-T-ONC-014556

A natural toxic furan isolated from a fungus-infected sweet potato (Ipomoea batatas) with potential antineoplastic activity. Ipomeanol is activated by mixed function oxidases in vivo to its epoxide form, an alkylating agent that covalently binds cell macromolecules. This agent causes cell death by a p53-independent mechanism.

Table 1. Record
IdentifierMLC-T-ONC-014556
FieldOncology and biomedicine
Synonyms4-ipomeanol
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014556",
  "term": "ipomeanol",
  "field": "Oncology and biomedicine",
  "definition": "A natural toxic furan isolated from a fungus-infected sweet potato (Ipomoea batatas) with potential antineoplastic activity. Ipomeanol is activated by mixed function oxidases in vivo to its epoxide form, an alkylating agent that covalently binds cell macromolecules. This agent causes cell death by a p53-independent mechanism.",
  "synonyms": [
    "4-ipomeanol"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ipomeanol/"
}

Record 9,552 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.