iPSC-derived MSCs CYP-001

{
  "id": "MLC-T-ONC-014564",
  "term": "iPSC-derived MSCs CYP-001",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of allogeneic mesenchymal stem cells (MSCs) derived from induced pluripotent stem cells (iPSCs), with potential immunomodulating activity. iPSCs are derived from one healthy adult donor and are expanded and differentiated into mesenchymoangioblasts (MCAs), which are further expanded and cultured, upon which MSCs are formed and further expanded. Upon intravenous administration and following allogeneic hematopoietic stem cell transplantation (HSCT), the iPSC-derived MSCs CYP-001 may attenuate and prevent acute graft versus host disease (aGvHD).",
  "synonyms": [
    "allogeneic MSCs CYP-001",
    "induced pluripotent stem cell-derived mesenchymal stem cells CYP-001"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ipsc-derived-mscs-cyp-001/"
}