MOPP regimen

{
  "id": "MLC-T-ONC-005500",
  "term": "MOPP regimen",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An abbreviation for a chemotherapy combination used alone or with radiation therapy to treat Hodgkin lymphoma. It includes the drugs mechlorethamine hydrochloride, vincristine sulfate (Oncovin), procarbazine hydrochloride, and prednisone. Also called MOPP.",
    "A chemotherapy regimen consisting of mechlorethamine, vincristine (Oncovin), procarbazine and prednisone, used alone or in combination with radiation therapy for the treatment of stage I-IV Hodgkin lymphoma. Due to the increased risk of gonadal toxicity, this regimen has been widely replaced by the ABVD regimen."
  ],
  "abbreviation": "MOPP",
  "synonyms": [
    "MOPP",
    "Mustargen-Oncovin-procarbazine-prednisone regimen",
    "mechlorethamine/prednisone/procarbazine/vincristine regimen"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/mopp-regimen/"
}