nadofaragene firadenovec-vncg

{
  "id": "MLC-T-ONC-015406",
  "term": "nadofaragene firadenovec-vncg",
  "field": "Oncology and biomedicine",
  "definition": "A replication-deficient recombinant adenovirus encoding human interferon alpha-2b with potential antineoplastic activity. Upon intravesical administration, nadofaragene firadenovec-vncg infects nearby tumor cells and expresses INF alpha-2b intracellularly which activates the transcription and translation of genes whose products mediate antiviral, antiproliferative, antitumor, and immune-modulating effects.",
  "abbreviation": "rAd-IFN",
  "synonyms": [
    "recombinant adenovirus-interferon SCH 721015",
    "nadofaragene firadenovec",
    "nadofaragene firadenovec/Syn3",
    "recombinant adenovirus-interferon with Syn3",
    "recombinant adenovirus-interferon/Syn3"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/nadofaragene-firadenovec-vncg/"
}