MLchartDataset catalogue

Notch signaling pathway inhibitor MK0752

Term · Oncology and biomedicine · MLC-T-ONC-015547

A synthetic small molecule with potential antineoplastic activity. MK0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated. The Notch signaling pathway plays an important role in cell-fate determination, cell survival, and cell proliferation.

Table 1. Record
IdentifierMLC-T-ONC-015547
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015547",
  "term": "Notch signaling pathway inhibitor MK0752",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic small molecule with potential antineoplastic activity. MK0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated. The Notch signaling pathway plays an important role in cell-fate determination, cell survival, and cell proliferation.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/notch-signaling-pathway-inhibitor-mk0752/"
}

Record 11,974 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.