odanacatib

{
  "id": "MLC-T-ONC-015590",
  "term": "odanacatib",
  "field": "Oncology and biomedicine",
  "definition": "An inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K, which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Cathepsin K, a tissue-specific cysteine protease that catalyzes degradation of bone matrix proteins such as collagen I/II, elastin, and osteonectin plays an important role in osteoclast function and bone resorption.",
  "synonyms": [
    "cathepsin K inhibitor MK0822"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/odanacatib/"
}