oncolytic Vaccinia virus PF-07263689

{
  "id": "MLC-T-ONC-015661",
  "term": "oncolytic Vaccinia virus PF-07263689",
  "field": "Oncology and biomedicine",
  "definition": "An engineered oncolytic vaccinia virus (VV), with potential immunomodulating and antineoplastic activities. Upon administration of oncolytic VV PF-07263689, the virus preferentially targets and infects tumor cells, thereby causing oncolysis. In turn, the lysed tumor cells release various tumor-associated antigens (TAAs), which induce an immune response against the tumor cells. This further kills tumor cells.",
  "synonyms": [
    "oncolytic VV PF-07263689"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/oncolytic-vaccinia-virus-pf-07263689/"
}