MLchartDataset catalogue

pyruvate kinase inhibitor TLN-232

Term · Oncology and biomedicine · MLC-T-ONC-016312

A synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells.

Table 1. Record
IdentifierMLC-T-ONC-016312
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-016312",
  "term": "pyruvate kinase inhibitor TLN-232",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pyruvate-kinase-inhibitor-tln-232/"
}

Record 13,916 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.