recombinant fowlpox-TRICOM vaccine

{
  "id": "MLC-T-ONC-007252",
  "term": "recombinant fowlpox-TRICOM vaccine",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A cancer vaccine made with a form of a chicken virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells. Also called rF-TRICOM.",
    "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding TRICOM. TRICOM is comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3) that may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells."
  ],
  "synonyms": [
    "rF-TRICOM",
    "rF-TRICOM (B7.1.iCAM1-LFA3-Fowlpox)"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-fowlpox-tricom-vaccine/"
}