Recombinant fowlpox-tyrosinase vaccine
Term · Oncology and biomedicine · MLC-T-ONC-016404
A recombinant fowlpox virus vaccine with potential antineoplastic activity. Binding to the melanoma antigen tyrosinase, recombinant fowlpox-tyrosinase vaccine generates cellular immune responses against melanoma cells expressing the tyrosinase antigen; this effect is enhanced by the co-administration of interleukin 2 (IL-2). Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.
| Identifier | MLC-T-ONC-016404 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | rF-TYR Vaccine |
| Synonyms | rF-TYR vaccine (Tyrosinase-Fowl Pox) |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-016404",
"term": "Recombinant fowlpox-tyrosinase vaccine",
"field": "Oncology and biomedicine",
"definition": "A recombinant fowlpox virus vaccine with potential antineoplastic activity. Binding to the melanoma antigen tyrosinase, recombinant fowlpox-tyrosinase vaccine generates cellular immune responses against melanoma cells expressing the tyrosinase antigen; this effect is enhanced by the co-administration of interleukin 2 (IL-2). Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.",
"abbreviation": "rF-TYR Vaccine",
"synonyms": [
"rF-TYR vaccine (Tyrosinase-Fowl Pox)"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/recombinant-fowlpox-tyrosinase-vaccine/"
}
Record 14,143 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.