recombinant interleukin-3

{
  "id": "MLC-T-ONC-016440",
  "term": "recombinant interleukin-3",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant form of interleukin-3, a cytokine produced by activated T-cells and mast cells involved in intercellular communication, hematopoiesis, and inflammation. IL-3 binds and activates specific receptors on hematopoietic cells and in the nervous system, triggering expression of specific genes via the Ras signaling pathway and through Jak2 activation. This agent stimulates the proliferation of pluripotent hematopoietic progenitor cells.",
  "abbreviation": "IL-3",
  "synonyms": [
    "mast cell colony-stimulating factor",
    "multipotential colony-stimulating factor",
    "interleukin-3",
    "eosinophil-mast cell growth factor",
    "erythrocyte burst-promoting factor"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-interleukin-3/"
}