MLchartDataset catalogue

milodistim

Term · Oncology and biomedicine · MLC-T-ONC-015186

A recombinant fusion protein derived from the coding sequences of two growth factors, interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF). Milodistim exhibits greater receptor binding affinity and colony stimulating activity than its parent cytokines. This agent stimulates proliferation of immature hematopoietic cells and allows the stimulation and expansion of multi-lineage hematopoiesis from immature bone marrow progenitor cells.

Table 1. Record
IdentifierMLC-T-ONC-015186
FieldOncology and biomedicine
Synonymspixykine; GM-CSF/IL-3 Fusion Protein; GM-CSF/IL3 Fusion Protein; Granulocyte-Macrophage Colony Stimulating Factor/Interleukin-3 Fusion Protein
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015186",
  "term": "milodistim",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant fusion protein derived from the coding sequences of two growth factors, interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF). Milodistim exhibits greater receptor binding affinity and colony stimulating activity than its parent cytokines. This agent stimulates proliferation of immature hematopoietic cells and allows the stimulation and expansion of multi-lineage hematopoiesis from immature bone marrow progenitor cells.",
  "synonyms": [
    "pixykine",
    "GM-CSF/IL-3 Fusion Protein",
    "GM-CSF/IL3 Fusion Protein",
    "Granulocyte-Macrophage Colony Stimulating Factor/Interleukin-3 Fusion Protein"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/milodistim/"
}

Record 11,064 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.