recombinant tumor necrosis factor family protein

{
  "id": "MLC-T-ONC-016464",
  "term": "recombinant tumor necrosis factor family protein",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant therapeutic agent which is chemically identical to or similar to one of a number of endogenous tumor necrosis factor (TNF) proteins. TNF family cytokines bind to and activate specific cell-surface receptors, thereby mediating inflammatory processes, cell proliferation, immunity, angiogenesis, and tumor cell cytotoxicity. One primary antitumor effect of TNFs involves stimulation of T cell-mediated antitumor cytotoxicity.",
  "abbreviation": "TNF",
  "synonyms": [
    "tumor necrosis factor",
    "Tumor Necrosis Factor Family Protein"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-tumor-necrosis-factor-family-protein/"
}