recombinant interferon gamma

{
  "id": "MLC-T-ONC-016434",
  "term": "recombinant interferon gamma",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant therapeutic agent which is chemically identical to or similar to the endogenous lymphokine interferon gamma (IFN-gamma) with antineoplastic, immunoregulatory, and antiviral activities. Therapeutic IFN-gamma binds to and activates the cell-surface IFN-gamma receptor, stimulating antibody-dependent cytotoxicity and enhances natural killer cell attachment to tumor cells. This agent also activates caspases, thereby inducing apoptosis in malignant cells.",
  "abbreviation": "IFN-G",
  "synonyms": [
    "gamma interferon"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-interferon-gamma/"
}