Recombinant interleukin-18

{
  "id": "MLC-T-ONC-016436",
  "term": "Recombinant interleukin-18",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-18 (IL-18). Produced primarily by macrophages, IL-18 induces the production of interferon-gamma (IFN-gamma), and enhances the activity of natural killer (NK) and cytotoxic T lymphocytes (CTL). As a potential immunotherapeutic agent, IL-18 displays antitumor effects in vitro and in animal models.",
  "abbreviation": "IL-18",
  "synonyms": [
    "interferon-gamma-inducing factor",
    "IFN-gamma-inducing factor"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-interleukin-18/"
}