recombinant interleukin-1-alpha

{
  "id": "MLC-T-ONC-016437",
  "term": "recombinant interleukin-1-alpha",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant agent which is chemically identical to or similar to the endogenous protein cytokine interleukin-1 (IL-1). The IL-1 precursor is produced by monocytes, activated macrophages, and other cell types; mature IL-1 is generated by proteolytic cleavage by proteases such as IL-1-beta converting enzyme (ICE). This agent enhances T cell proliferation and B cell growth and differentiation and induces the expression of proinflammatory cytokines.",
  "synonyms": [
    "interleukin-1-alpha"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-interleukin-1-alpha/"
}