Synthetic glioblastoma tumor-associated peptides vaccine therapy APVAC1

{
  "id": "MLC-T-ONC-016940",
  "term": "Synthetic glioblastoma tumor-associated peptides vaccine therapy APVAC1",
  "field": "Oncology and biomedicine",
  "definition": "A personalized peptide-based cancer vaccine comprised of five to ten peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB tumor-associated peptides vaccine therapy APVAC1 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the tumor associated peptides, and results in decreased GB growth. The peptides are derived from a glioma actively-personalized vaccine consortium (GAPVAC) warehouse and are specifically selected based on the patient's expression of tumor-associated antigens.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/synthetic-glioblastoma-tumor-associated-peptides-vaccine-therapy-apvac1/"
}