toll-like receptor 7 agonist DSP-0509

{
  "id": "MLC-T-ONC-017231",
  "term": "toll-like receptor 7 agonist DSP-0509",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic, small molecule, toll-like receptor (TLR) 7 agonist, with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, TLR7 agonist DSP-0509 activates TLR7, thereby inducing type I interferon secretion and activation of cytotoxic T-lymphocyte (CTL)-mediated anti-tumor immune responses, thereby reducing tumor cell growth. TLR7 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity.",
  "synonyms": [
    "TLR7 agonist DSP-0509"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/toll-like-receptor-7-agonist-dsp-0509/"
}