tri-specific NK cell engager CC-92328
Term · Oncology and biomedicine · MLC-T-ONC-017333
A tri-specific natural killer (NK) cell engager, with potential immunomodulating and antineoplastic activities. Upon administration, the tri-specific NK cell engager CC-92328 binds to as of yet unelucidated proteins expressed on both cancer cells and NK cells, thereby bringing cancer cells and NK cells together. This stimulates the NKs and allows for NK-mediated cancer cell killing. In addition, the NKs activate T and B cells, and enhance a cytotoxic T-lymphocyte (CTL) immune response against cancer cells.
| Identifier | MLC-T-ONC-017333 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | tri-specific NK cell engager therapeutic agent CC-92328; TriNKET CC-92328 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-017333",
"term": "tri-specific NK cell engager CC-92328",
"field": "Oncology and biomedicine",
"definition": "A tri-specific natural killer (NK) cell engager, with potential immunomodulating and antineoplastic activities. Upon administration, the tri-specific NK cell engager CC-92328 binds to as of yet unelucidated proteins expressed on both cancer cells and NK cells, thereby bringing cancer cells and NK cells together. This stimulates the NKs and allows for NK-mediated cancer cell killing. In addition, the NKs activate T and B cells, and enhance a cytotoxic T-lymphocyte (CTL) immune response against cancer cells.",
"synonyms": [
"tri-specific NK cell engager therapeutic agent CC-92328",
"TriNKET CC-92328"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/tri-specific-nk-cell-engager-cc-92328/"
}
Record 16,743 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.