tyrosine kinase inhibitor OSI-930

{
  "id": "MLC-T-ONC-017379",
  "term": "tyrosine kinase inhibitor OSI-930",
  "field": "Oncology and biomedicine",
  "definition": "A selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tyrosine-kinase-inhibitor-osi-930/"
}