tyrosine kinase inhibitor TL-895
Term · Oncology and biomedicine · MLC-T-ONC-017380
An orally bioavailable inhibitor of tyrosine kinase, with potential anti-inflammatory and antineoplastic activities. Upon oral administration, tyrosine kinase inhibitor TL-895 targets, binds to, and inhibits tyrosine kinase. This may result in the inhibition of tumor angiogenesis and cell proliferation, and the inhibition of immune-mediated inflammatory processes. Tyrosine kinases are upregulated in many tumor cells and play important roles in tumor cell proliferation and metastasis. In addition, they play important roles in the activation of leukocytes and in many immune-mediated inflammatory and autoimmune conditions.
| Identifier | MLC-T-ONC-017380 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | TKI TL-895 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-017380",
"term": "tyrosine kinase inhibitor TL-895",
"field": "Oncology and biomedicine",
"definition": "An orally bioavailable inhibitor of tyrosine kinase, with potential anti-inflammatory and antineoplastic activities. Upon oral administration, tyrosine kinase inhibitor TL-895 targets, binds to, and inhibits tyrosine kinase. This may result in the inhibition of tumor angiogenesis and cell proliferation, and the inhibition of immune-mediated inflammatory processes. Tyrosine kinases are upregulated in many tumor cells and play important roles in tumor cell proliferation and metastasis. In addition, they play important roles in the activation of leukocytes and in many immune-mediated inflammatory and autoimmune conditions.",
"synonyms": [
"TKI TL-895"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/tyrosine-kinase-inhibitor-tl-895/"
}
Record 16,877 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.