WT-1 analogue peptide vaccine

{
  "id": "MLC-T-ONC-017577",
  "term": "WT-1 analogue peptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A peptide vaccine containing a human Wilms tumor 1 (WT-1) protein-derived epitope with potential antineoplastic activity. Vaccination with the WT-1 analogue peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against WT-1 expressing cells, resulting in tumor cell lysis and inhibition of tumor cell proliferation. WT-1, a zinc finger transcription factor, is overexpressed in most types of leukemia and in some solid cancers.",
  "synonyms": [
    "WT-1 vax"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/wt-1-analogue-peptide-vaccine/"
}